Clinical Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required) (342124)

US Dept. of Health & Human Services: National Institutes of Health (NIH)

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Next deadline: Oct 11, 2023 (Full proposal)

Later deadlines: Jan 13, 2024 (Letter of inquiry), Feb 13, 2024 (Full proposal), May 11, 2024 (Letter of inquiry), Jun 11, 2024 (Full proposal), Sep 11, 2024 (Letter of inquiry), Oct 11, 2024 (Full proposal), Jan 11, 2025 (Letter of inquiry), Feb 11, 2025 (Full proposal), May 11, 2025 (Letter of inquiry), Jun 11, 2025 (Full proposal), Aug 11, 2025 (Letter of inquiry), Sep 11, 2025 (Full proposal)

Grant amount: Unspecified amount

Fields of work: Science Health & Medicine Biomedical informatics Hematological Systems Respiratory Diseases & Systems Cardiovascular Diseases & Systems

Applicant type: Government Entity, Nonprofit, For-Profit Business, Indigenous Group

Funding uses: Research, Training / Capacity Building

Location of project: Anywhere in the world

Location of residency: Anywhere in the world


NOTE: All types of non-AIDS applications allowed for this funding opportunity announcement are due on these dates: February 10, 2023, June 13, 2023, October 11, 2023, February 13, 2024, June 11, 2024, October 11, 2024, February 11, 2025, June 11, 2025. All applications are due by 5:00 PM local time of applicant organization. 

All types of AIDS and AIDS-related applications allowed for this funding opportunity announcement are due on these dates: January 11, 2023, May 11, 2023, September 11, 2023, January 11, 2024, May 10, 2024, September 11, 2024, January 10, 2025, May 12, 2025, September11, 2025. All applications are due by 5:00 PM local time of applicant organization. 

This Funding Opportunity Announcement (FOA) supports applications to develop and implement a Clinical Coordinating Center (CCC) for investigator-initiated multi-site clinical trials including efficacy, comparative effectiveness, pragmatic and/or implementation research clinical trials. Trials for which this FOA applies must be relevant to the research mission of the NHLBI and meet the NIH definition of a clinical trial (see NOT-OD-15-015). For additional information about the mission, strategic vision, and research priorities of the NHLBI, applicants are encouraged to consult the NHLBI website.This FOA will utilize a bi-phasic, milestone-driven cooperative agreement mechanism of award and runs in parallel with a companion FOA that encourages applications for a collaborating Data Coordinating Center (PAR-22-NNN). The objective of the CCC application is to present the scientific rationale for the clinical trial and a comprehensive scientific and operational plan that describes it. The application should address project management, subject recruitment and retention, performance milestones, scientific conduct of the trial, and dissemination of results. Both a CCC application and a collaborating Data Coordinating Center (DCC) application must be submitted on the same application due date for consideration by NHLBI. Applicants are strongly encouraged to contact the appropriate Scientific/Research contact prior to submitting an application.

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This page was last reviewed July 16, 2023 and last updated July 16, 2023