Cooperative Agreement for In Vivo High-Resolution Imaging for Inner Ear Visualization (U01 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)

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Next deadline: May 1, 2024 (Letter of inquiry)

Later deadlines: Jun 3, 2024 (Full proposal), Sep 1, 2024 (Letter of inquiry), Oct 1, 2024 (Full proposal), Jan 3, 2025 (Letter of inquiry), Feb 3, 2025 (Full proposal)

Grant amount: Up to US $2,500,000

Fields of work: Biomedical Imaging Hearing Disorders & Audiology

Applicant type: Nonprofit, Government Entity, Indigenous Group, For-Profit Business

Funding uses: Research

Location of project: Anywhere in the world

Location of residency: Anywhere in the world


NOTE: All applications are due by 5:00 PM local time of applicant organization. Letters of Intent are due 30 days prior to the full proposal deadline.

This funding opportunity aims to support high risk clinical trials for the development of in vivo high-resolution structural and functional imaging technologies for the living human inner ear. Proposed projects should focus on improving the resolution of current imaging techniques or developing new imaging techniques that can visualize inner ear structures in vivo with significantly greater detail and accuracy than currently possible. Structural and functional aspects, including visualizing dynamic elements, are important to developing new and improved techniques. Projects may also focus on developing new imaging probes or contrast agents that can enhance visualization of the inner ear structures. Research supported in response to this RFA is expected to significantly advance the ability to visualize auditory and vestibular components, such as hair cells, otoliths, membranes, ions, and vasculature, in detail in awake patients in a clinical setting using non-invasive techniques. To achieve this goal, a multidisciplinary team approach that takes advantage of the expertise of each team member is highly encouraged. Studies in humans must be proposed to develop,advance, or test the needed technology. Any intermediate studies must articulate a clear path of the proposed methodology to application in awake humans or define the limitations and the usefulness in anesthetized humans.

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US Dept. of Health & Human Services: National Institutes of Health (NIH)

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This page was last reviewed November 13, 2023 and last updated November 13, 2023