Development and Validation of Harmonized Methodologies to Measure NAD+ and Related Metabolites in Clinical Trials (U01 Clinical Trial Required)

US Dept. of Health & Human Services: National Institutes of Health (NIH)

Note: This grant page has been archived and is very likely out of date.

Deadline: The deadline for this grant has passed

Grant amount: Unspecified amount

Fields of work: Aging/Gerontology Cell Biology

Applicant type: Nonprofit, Government Entity, Indigenous Group, For-Profit Business

Funding uses: Research

Location of project: United States, American Samoa, Guam, Northern Mariana Islands, Puerto Rico Show all

Location of residency: Preferred: United States, American Samoa, Guam, Northern Mariana Islands, Puerto Rico, Virgin Islands Other eligible locations: Anywhere in the world

Overview:

NOTE: All applications are due by 5:00 PM local time of applicant organization. 

This Notice of Funding Opportunity (NOFO) invites applications to develop and validate the standardized protocols for measuring nicotinamide adenine dinucleotide (NAD+) and related metabolites levels in humans, including sample collection and storage, assays calibration, and standardization of measurements across different types of samples such as plasma, tissue, or serum extracts, and validation of these protocols. Limited preclinical animal studies could be proposed by the applicants, if such studies are integral part of the applications and if they are needed to test the select elements of the standardized protocols in animal models before such protocols could be tested in humans. The proposed studies will be funded by individual awards, but the awardees will be required to interact as a network to exchange information, discuss their progress, pitfalls and issues arising during studies implementation.

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US Dept. of Health & Human Services: National Institutes of Health (NIH)
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This page was last reviewed July 09, 2023 and last updated July 09, 2023