Mechanistic Research on Neuromodulation for Substance Use Disorders Treatment (R61/R33 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)

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Next deadline: Aug 14, 2024

Later deadlines: Jan 16, 2025, Aug 14, 2025, Jan 16, 2026, Aug 14, 2026

Grant amount: Up to US $600,000

Fields of work: Addiction & Substance Use Disorders Neuroscience

Applicant type: Nonprofit, Government Entity, Indigenous Group, For-Profit Business

Funding uses: Research

Location of project: Anywhere in the world

Location of residency: Anywhere in the world


NOTE: All applications are due by 5:00 PM local time of applicant organization.  Letters of Intent are optional but encouraged and are due 30 days prior to the full proposal deadline. 

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage clinical research that will identify and validate novel targets for non-invasive brain stimulation (NIBS) and SUD-relevant neurobiological, cognitive, and behavioral responses to NIBS that precede clinical outcomes like reduced craving or drug use. Applications are expected to be exploratory and developmental in nature. As such, these studies may involve considerable risk of failure but may lead to a breakthrough in a particular area that could have a major impact on SUD research involving NIBS. This NOFO uses a R61/R33 Phased Innovation award activity code to support applications that propose mechanistic studies designed to understand a behavior or biological process, the pathophysiology of a disease, or the mechanism of action of an intervention. In addition, applications must meet the NIH definition of a clinical trial. NIH defines a clinical trial as A research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include placebo or other control) to evaluate the effects of those interventions on health-related biomedical or behavioral outcomes. (NOT-OD-15-015)

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US Dept. of Health & Human Services: National Institutes of Health (NIH)

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This page was last reviewed October 15, 2023 and last updated October 15, 2023