Prospective Observational Comparative Effectiveness Research in Clinical Neurosciences (UG3/UH3 Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)

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Predicted Deadline
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Next predicted deadline: Oct 18, 2023 (Full proposal)

Later predicted deadlines: Dec 7, 2023 (Letter of inquiry), Jan 7, 2024 (Full proposal), Jan 20, 2024 (Letter of inquiry), Feb 20, 2024 (Full proposal), Apr 7, 2024 (Letter of inquiry), May 7, 2024 (Full proposal), May 18, 2024 (Letter of inquiry), Jun 18, 2024 (Full proposal), Aug 7, 2024 (Letter of inquiry), Sep 7, 2024 (Full proposal), Sep 18, 2024 (Letter of inquiry), Oct 18, 2024 (Full proposal), Dec 7, 2024 (Letter of inquiry), Jan 7, 2025 (Full proposal), Jan 19, 2025 (Letter of inquiry), Feb 19, 2025 (Full proposal), Apr 7, 2025 (Letter of inquiry), May 7, 2025 (Full proposal)

Grant amount: Unspecified amount

Fields of work: Neuroscience Neurological Diseases & Disorders Stroke

Applicant type: Organizations

Funding uses: Research

Location of project: Anywhere in the world

Location of residency: Anywhere in the world


NOTE: All types of non-AIDS applications allowed for this funding opportunity announcement are due on these dates: February 17, 2023, June 19, 2023, October 18, 2023, February 20, 2024, June 18, 2024, October 18, 2024, February 19, 2025 by 5:00 PM local time of the applicant organization. All types of AIDS and AIDS-related applicants allowed for this funding opportunity announcement are due on these dates: January 07, 2023, May 07, 2023, September 07, 2023, January 07, 2024, May 07, 2024, September 07, 2024, January 07, 2025, May 07, 2025 by 5:00 PM local time of the applicant organization.

The purpose of this Funding Opportunity Announcement (FOA) is to encourage grant applications for investigator-initiated prospective observational comparative effectiveness research (CER) to the National Institute of Neurological Disorders and Stroke (NINDS). The study must address questions within the mission and research interests of the NINDS and may evaluate preventive strategies, diagnostic approaches, or interventions including drugs, biologics, and devices, or surgical, behavioral, and rehabilitation therapies. Information about the mission and research interests of the NINDS can be found at the NINDS website. Studies proposed should provide a cost-effective means of collecting data with a meaningful bearing on current clinical practice. Awards made under this FOA will initially support a milestone-driven planning phase (UG3) for up to 2 years, with possible transition to a observational study phase of up to five years (UH3). Only UG3 projects that have met the scientific milestones and feasibility requirements may transition to the UH3 phase. The UG3/UH3 application must be submitted as a single application, following the instructions described in this FOA. The UG3 phase for observational studies will permit both scientific and operational planning activities. Scientific planning activities include small-scale data collection to assess the feasibility and/or acceptability of data collection, storage, and planned analyses. Operational planning activities include, at a minimum, development of recruitment and retention strategies, case report forms, data management system and other tools for data and quality management. The UH3 phase of the award will support the conduct of investigator-initiated observational study.

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This page was last reviewed May 09, 2023 and last updated May 09, 2023