Protective Strategies to Reduce Amyloid Related Imaging Abnormalities (ARIA) After Anti-Amyloid Beta Immunotherapy (R01 - Clinical Trial Not Allowed)

US Dept. of Health & Human Services: National Institutes of Health (NIH)

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Next deadline: Sep 4, 2024 (Letter of inquiry)

Later deadlines: Oct 4, 2024 (Full proposal), Oct 4, 2024 (Letter of inquiry), Nov 4, 2024 (Full proposal)

Grant amount: Up to US $2,500,000

Fields of work: Cell Biology Neuroscience Hematological Systems

Applicant type: Nonprofit, Government Entity, Indigenous Group, For-Profit Business

Funding uses: Research

Location of project: United States, American Samoa, Guam, Northern Mariana Islands, Puerto Rico Show all

Location of residency: United States, American Samoa, Guam, Northern Mariana Islands, Puerto Rico Show all

Overview:

NOTE: The following deadlines apply to standard grant applications (due by 5:00 pm  local time of applicant organization): October 4, 2024. The following deadlines apply to Renewal/Resubmission/Revision grant applications (due by 5:00 pm local time of applicant organization): November 4, 2024.

This initiative is designed to promote discovery of cellular and molecular mechanisms that underlie brain blood vessels responses to passive anti-beta-amyloid immunotherapy that result in amyloid-related imaging abnormalities (ARIA). The goal is to establish an understanding of molecular mechanisms that can be targeted to protect the blood brain barrier (BBB), and thus the brain blood vessels, during therapeutic interventions that target beta-amyloid.

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US Dept. of Health & Human Services: National Institutes of Health (NIH)
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This page was last reviewed April 11, 2024 and last updated April 11, 2024