Seeking Products to Address Social Needs impacting Substance Use Disorders (SUD) (R43/R44 Clinical Trial Optional)

US Dept. of Health & Human Services: National Institutes of Health (NIH)

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Next deadline: Mar 13, 2025

Later deadlines: Mar 13, 2026

Grant amount: Up to US $2,268,752

Fields of work: Addiction & Substance Use Disorders Medical Technology & Devices

Applicant type: For-Profit Business

Funding uses: Project / Program, Research

Location of project: United States, American Samoa, Guam, Northern Mariana Islands, Puerto Rico Show all

Location of residency: United States, American Samoa, Guam, Northern Mariana Islands, Puerto Rico Show all


NOTE: Optional but encouraged Letters of Intent are due thirty days prior to application due date. All applications for Letters of Intent and Full Proposals are due by 5:00 PM local time of applicant organization. 

The purpose of this funding opportunity is to support applications from small business concerns (SBCs) to develop technologies for commercialization to address health-related social needs that impact substance use disorders (SUD), excluding alcohol use disorder.

A variety of products addressing the individual-level factors of HRSN should be considered to confront SUD. Additionally, technology, such as telemedicine and mobile health applications, provide an opportunity to address HRSN with the ability to provide tested, accessible, and ongoing solutions for individuals who are the most at-risk for these risk factors that impact SUD. According to SAMHSA, technology has several advantages in addressing Substance SUD including decreased waiting periods, decreased stigma impact, and increased privacy. The advantages of technology are also exhibited in its capability to make treatment services more accessible and convenient which can aid to improve SUD outcomes and reduce disparities.  

Regarding this NOFO, a product is any source of value for the end-users and customers. A product can be a physical/tangible device as well as digital services, software as a service, or non-physical/non-tangible products (including but not limited to digital applications, digital platforms, or service models). These and other comparable examples could be considered eligible products. Products can be the result of original scientific research, recycled existing technology for SUD, extension of an observation into SUD area, development of a new business model or distribution/delivery channel that reveals currently unseen value, or the delivery of a product or service to disregarded consumers.  

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US Dept. of Health & Human Services: National Institutes of Health (NIH)

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This page was last reviewed October 15, 2023 and last updated October 15, 2023